What causes SSTI?

What causes SSTI?

Although Staphylococcus aureus and beta-hemolytic streptococci represent the traditional culprits in SSTI [5], more recently Gram-negative organisms, as well as mixed pathogens (both Gram-negative and Gram-positive bacteria), have become significant causes of acute skin infections [5–8].

Which is the major organism causing skin and soft tissue infections?

Bacteria live on and around the skin and are the most common cause of SSTIs as they can enter your body in many ways, including through punctures, burns, small cuts, scrapes, and surgical site wounds. The most common bacteria that cause these infections are Staphylococcus aureus (Staph) and Streptococcus (Strep).

What are the risk factors of cellulitis?

Several factors increase the risk of cellulitis:

• Injury. Any cut, fracture, burn or scrape gives bacteria an entry point.
• Weakened immune system.
• Skin conditions.
• Long-term (chronic) swelling of the arms or legs (lymphedema).
• History of cellulitis.
• Being overweight.

Is cellulitis a SSTI?

Common Skin and Soft Tissue Infections Common SSTIs include: Abscesses. Cellulitis.

Which is the most common pathogen?

10 most common pathogens leading to HAIs

• Coagulase-negative staphylococci 15%
• Staphylococcus aureus 15%
• Enterococcus species 12%
• Candida species 11%
• Escherichia coli 10%
• Pseudomonas aeruginosa 8%
• Klebsiella pneumoniae 6%
• Enterobacter species 5%

Is cellulitis more common in the obese?

Skin infections and cellulitis Obesity is associated with a wide range of skin diseases. Case–control studies indicate an increased risk of cellulitis and skin infections in the overweight93 and obese.

Does cellulitis weaken your immune system?

Cellulitis is a bacterial infection of the deep layers of your skin and the tissue beneath your skin. Although it’s common in adults and children, Without treatment the infection can spread quickly and permanently damage your immune system.

How common is pyomyositis?

Pyomyositis is a rare bacterial infection of the muscle that usually results in an abscess. It’s most common in your thigh muscles. Pyomyositis can be difficult to diagnose, and symptoms usually include fever and muscle pain. Healthcare providers often treat it with antibiotics.

What are the risk factors of pyomyositis?

Predisposing factors — Predisposing factors associated with pyomyositis include immunodeficiency, trauma, injection drug use, concurrent infection, and malnutrition [2,8-12]. Immunodeficiency — Immunodeficiency has been implicated in the development of pyomyositis in both temperate and tropical climates.

What is the prevalence of ABSSSI?

ABSSSI are common and encompass a variety of disease presentations and severity. Antimicrobial resistance among both Gram-positive and Gram-negative bacteria has increased significantly with methicillin resistance among S. aureusapproaching 60% in hospitals and becoming more frequent in the community as well.

What is the difference between usssi and cSSSI?

The uncomplicated category (uSSSI) is normally only caused by Staphylococcus aureus and Streptococcus pyogenes, whereas the complicated category (cSSSI) might also be caused by a number of other pathogens. In cSSSI, the pathogen is known in only about 40% of cases.

What is the pathophysiology of cSSSI?

Primary cSSSI’s resulting from single bacterial species and secondary bacterial infections in patients suffering from skin conditions due to autoimmune conditions (eczema) or other microbial causes (viruses, fungi and parasites) have been reported in the literature.

What does cSSSI stand for?

It often requires treatment by antibiotics. It may be complicated skin and skin structure infection (cSSSI) or uncomplicated skin and skin structure infection.