What is difference between morphine and pethidine?

What is difference between morphine and pethidine?

Morphine is the standard opium-based analgesic with well-known analgesic effects and side effects. Meperidine (pethidine) is another opioid, but the use of meperidine is not very popular in countries such as the USA and Canada, however it is still used in Iran for pain management in the ED.

Is pethidine stronger then morphine?

Pethidine is now rarely used as it is no more effective than morphine, and is associated with an increased risk of adverse effects, such as vomiting and seizures.

Which is better Demerol or morphine?

Many people also compare Demerol vs morphine for their potency and effectiveness. Demerol is not stronger than morphine, but actually, Demerol is seven to 10 times less potent than morphine.

Which is stronger pethidine or tramadol?

Conclusions. Tramadol provided adequate analgesia and it was more effective than pethidine to at least six hours for the studied animals. At the higher dose (4 mg/kg) tramadol is probably more effective, since rescue analgesia was not necessary.

Is pethidine used today?

Pethidine is now less frequently used because newer, safer opioids are available. Pethidine is sometimes to used to reduce labour pain in childbirth. Pethidine is considered highly addictive and so is not prescribed on an ongoing basis, or in the treatment of persistent pain in chronic conditions.

Why is morphine given during labour?

Morphine. Morphine is a strong painkiller given by injection.It helps reduce the severity of pain, but does not take it away completely. It can take up to 20 minutes to work and effect lasts three hours or more. Morphine is preferable to pethidine because it lasts longer and has fewer side effects.

Is morphine OK during labour?

Intramuscular/Intravenous/Inhaled Pain Relievers Narcotics are sometimes offered in early labour. Morphine is the most common narcotic for this purpose and may be given intravenously or intramuscularly. If given intramuscularly, pain relief takes effect within 20 to 30 minutes and lasts from two to four hours.

What are the side effects of morphine and pethidine?

No significant differences in the incidence of side effects between groups were found with the exception of more pruritus reported in the group given morphine. Patients who experienced vomiting or pruritus reported a greater intensity of these side effects if receiving morphine and fentanyl than if receiving pethidine.

Is pethidine better than morphine for biliary spasm?

Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction, and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects.

What is pethidine used to treat?

Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous, or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975, 60% of doctors prescribed it for acute pain

Is pethidine a hazardous or harmful drug?

In data from the U.S. Drug Abuse Warning Network, mentions of hazardous or harmful use of pethidine declined between 1997 and 2002, in contrast to increases for fentanyl, hydromorphone, morphine, and oxycodone. The number of dosage units of pethidine reported lost or stolen in the U.S. increased 16.2% between 2000 and 2003, from 32,447 to 37,687.