What is meant by hydrodynamic radius?

What is meant by hydrodynamic radius?

The effective radius of an ion in a solution measured by assuming that it is a body moving through the solution and resisted by the solution’s viscosity. If the solvent is water, the hydrodynamic radius includes all the water molecules attracted to the ion.

What is hydrodynamic radius of protein?

The radius of gyration (Rg) is the root-mean-squared distance of all the atoms in the molecule from the protein center of mass, while the hydrodynamic radius (Rh) can be defined as the radius of a sphere that has the same diffusion coefficient as the protein molecule.

What is hydrodynamic radius of polymer?

Note that in biophysics, hydrodynamic radius refers to the Stokes radius, or commonly to the apparent Stokes radius obtained from size exclusion chromatography. The theoretical hydrodynamic radius. arises in the study of the dynamic properties of polymers moving in a solvent.

What affects hydrodynamic radius?

For proteins, this is largely determined by the molecular weight, but shape also plays a role, with compact, well-folded proteins diffusing faster than extended, poorly folded proteins, and thus having a smaller hydrodynamic radius.

Why is hydrodynamic radius important?

The surface hydrophobicity (So), intrinsic viscosity (IV) and hydrodynamic radius (Rh) are important indicators of the structures of proteins, and can be used to evaluate the effect of processing on the denaturation and aggregation of proteins [12] .

What is hydrodynamic size in DLS?

Note that the diameter that is measured in DLS is a value that refers to how a particle diffuses within a fluid so it is referred to as a hydrodynamic diameter. The diameter that is obtained by this technique is the diameter of a sphere that has the same translational diffusion coefficient as the particle.

What is hydrodynamic nanoparticle size?

The hydrodynamic diameter for small particles increases from 7.1 ± 1.9 nm to 13.2 ± 3.3 nm as the MNP concentration increases from 25 to 50 mg/L.

What is hydrodynamic friction?

friction produced by the viscosity of a liquid in motion.

What is hydrodynamic diameter of nanoparticles?

What is hydrodynamic volume?

Hydrodynamic volume – the volume of a polymer coil when it is in solution. This can vary for a polymer depending on how well it interacts with the solvent, and the polymer’s molecular weight.

What is DLS analysis?

Particle size can be determined by measuring the random changes in the intensity of light scattered from a suspension or solution. This technique is commonly known as dynamic light scattering (DLS), but is also called photon correlation spectroscopy (PCS) and quasi-elastic light scattering (QELS).