What are 5 classes of antiarrhythmic drugs?

What are 5 classes of antiarrhythmic drugs?

What are 5 classes of antiarrhythmic drugs?

Vaughan-Williams classification

  • Class 1: sodium channel blockers.
  • Class 2: beta-blockers.
  • Class 3: potassium.
  • Class 4: calcium channel blockers.
  • Class 5: miscellaneous agents that cannot be categorized into the above groups.

How are antiarrhythmic drugs classified?

Class I agents block sodium channels. Class II agents are Beta blockers. Class III agents prolong the cardiac action potential. Class IV agents are calcium channel blockers.

What are the classes of antiarrhythmic drugs give examples?

Overview

Classes of antiarrhythmic drugs
Class Examples
Class I antiarrhythmics Class IB antiarrhythmics Lidocaine Mexiletine Phenytoin
Class IC antiarrhythmics Flecainide Propafenone
Class II antiarrhythmic drugs Metoprolol Esmolol (short acting) Propranolol Atenolol Timolol Carvedilol Sotalol

What are Class 1 antiarrhythmics used for?

Quinidine, disopyramide, procainamide, lidocaine, mexiletine, flecainide, and propafenone are all class I antiarrhythmic drugs (table 1) used for the treatment of various atrial and ventricular arrhythmias.

What are Class 3 antiarrhythmic drugs?

Class 3 antiarrhythmics are drugs that block cardiac Cardiac Total Anomalous Pulmonary Venous Return (TAPVR) tissue K channels Channels The Cell: Cell Membrane . The medications in this class include amiodarone….Medications within this drug class

  • Amiodarone.
  • Dronedarone.
  • Sotalol.
  • Ibutilide.
  • Dofetilide.
  • Bretylium.

What are Class 4 antiarrhythmic drugs?

Indications

Drug class Examples
Dihydropyridines Pulmonary Hypertension Drugs Nifedipine, nicardipine, amlodipine It is effective in the treatment of angina pectoris and hypertension. Hypertension Drugs , felodipine, nimodipine
Benzothiazepines Diltiazem
Phenylalkylamines Verapamil

What are the 4 classes of antiarrhythmic drugs?

Antiarrhythmic drug classes:

  • Class I – Sodium-channel blockers.
  • Class II – Beta-blockers.
  • Class III – Potassium-channel blockers.
  • Class IV – Calcium-channel blockers.
  • Miscellaneous – adenosine. – electrolyte supplement (magnesium and potassium salts) – digitalis compounds (cardiac glycosides)

Is amlodipine an antiarrhythmic?

Dihydropyridines, like amlodipine, nicardipine, and nifedipine, are highly selective for calcium channels on the vascular smooth muscle tissue; so they’re primarily used to treat hypertension. On the other hand, non-dihydropyridines are the class IV antiarrhythmics and they include verapamil and diltiazem.

Which of the following is a Class 4 antiarrhythmic drug?

What is a Class 1C drug?

Background. Class 1C antiarrhythmic drugs (AADs) are effective first‐line agents for atrial fibrillation (AF) treatment. However, these agents commonly are avoided in patients with known coronary artery disease (CAD), due to known increased risk in the postmyocardial infarction population.

What is a Class III antiarrhythmic?

Class III antiarrhythmic drugs act by blocking repolarising currents and thereby prolong the effective refractory period of the myocardium. This is believed to facilitate termination of re-entry tachyarrhythmias. This class of drugs is developed for treatment of both supraventricular and ventricular arrhythmias.

What are the Class 2 antiarrhythmics?

Class 2 antiarrhythmics include beta-blockers, which exert their therapeutic effects by blocking epinephrine….Classification

  • Acebutolol.
  • Atenolol.
  • Betaxolol.
  • Bisoprolol.
  • Esmolol. Esmolol Antiadrenergic Drugs.
  • Metoprolol. Antiadrenergic Drugs.