What are examples of binding proteins?

What are examples of binding proteins?

Examples include:

• DNA-binding protein. Single-strand binding protein. Telomere-binding protein.
• RNA-binding protein. Poly(A)-binding protein. Nuclear cap-binding protein complex.
• CREB-binding protein.
• Calcium-binding protein. Calcium-binding protein 1. S100 calcium-binding protein A1.
• TATA-binding protein.
• Actin-binding protein.

What drug is Proteinbound?

Protein binding of drugs is the formation of reversible complexes between drugs and blood components, which may include plasma proteins and the constituents of red cells. The main determinants of protein binding are: Number of available binding sites (i.e. protein concentration)

Is androgen binding protein a hormone?

In these species it is thought to function to concentrate androgens in the seminiferous tubules and deliver the steroid hormone to developing spermatocytes and spermatids. ABP is now known to be a homolog of sex hormone binding globulin, SHBG, the serum binding protein for androgens and estrogens (section III.

Which is a DNA binding protein?

Within chromosomes, DNA is held in complexes with structural proteins. These proteins organize the DNA into a compact structure called chromatin. In eukaryotes, this structure involves DNA binding to a complex of small basic proteins called histones.

How many DNA-binding proteins are there?

Venn diagram of DNA binding and of RNA binding proteins identified in high-throughput studies defining the human mRNA2 and dsDNA3 interactomes13,14. There are 407 proteins found in both studies, indicating that they may bind both mRNA and dsDNA.

What are protein bonds?

Within a protein, multiple amino acids are linked together by peptide bonds, thereby forming a long chain. Peptide bonds are formed by a biochemical reaction that extracts a water molecule as it joins the amino group of one amino acid to the carboxyl group of a neighboring amino acid.

How many Igfbp are there?

The IGFBP family is evolutionarily ancient and highly conserved in vertebrates (11, 14–16). The six types of IGFBPs have been designated IGFBP-1 through IGFBP-6.

Is vancomycin highly protein-bound?

The protein binding of vancomycin has been reported to range from less than 10 percent to 82 percent. We examined the binding of vancomycin in 34 patients (14 intravenous drug abusers, 10 burn patients, and 10 control patients) with Staphylococcus aureus infections.

Is digoxin highly protein-bound?

Digoxin is a cardioactive drug that is only 25% bound to serum proteins, mainly albumin. Therefore, monitoring free digoxin is not indicated for patients with uremia, liver disease, or any other pathophysiological conditions that may cause hypoalbuminemia.

What cells produce androgen binding proteins?

Androgen-binding protein (ABP) is synthesized by the Sertoli cell in the testis, where ~80% is secreted into the luminal fluid and the other ~20% is secreted into the interstitial compartment and taken up into the systemic circulation.