What causes hyperkeratosis?

What causes hyperkeratosis?

Causes and types Pressure-related hyperkeratosis occurs as a result of excessive pressure, inflammation or irritation to the skin. When this happens, the skin responds by producing extra layers of keratin to protect the damaged areas of skin. Non-pressure related keratosis occurs on skin that has not been irritated.

What is acanthosis hyperkeratosis?

Acanthosis nigricans (AN) is a skin condition characterized by abnormally increased coloration (hyperpigmentation) and “velvety” thickening (hyperkeratosis) of the skin, particularly of skin fold regions, such as of the neck and groin and under the arms (axillae).

How serious is hyperkeratosis?

Symptoms of Severe Hyperkeratosis Symptoms include significant heavy callus on the bottom of the feet which can crack and cause considerable discomfort and will occasionally lead to infection. It can also affect the toenails causing thickening and crumbling and in some cases it can affect the hands.

What is the treatment for hyperkeratosis?

Warts and actinic keratosis may be removed with cryosurgery or laser therapy. Topical agents used in the treatment of hyperkeratosis may include: Salicylic acid to break up the keratin, causing the thick skin to soften and be shed, thus reducing the thickness of the skin.

What does acanthosis mean?

Acanthosis is term pathologists use to describe an increased number of specialized squamous cells on the surface of a tissue. Acanthosis is commonly seen in the top layer of the skin called the epidermis. Acanthosis can also be seen in the epithelium that lines the inside of the mouth and throat.

Can hyperkeratosis be cured?

This and other inherited forms of hyperkeratosis can’t be cured. Medications that include a form of vitamin A can sometimes improve symptoms. There is also research being done to use gene therapy to help treat this condition.